Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690598 | 0.80 | ALDH1A1 (0.53) | ALDH1A1HPGDHSD11B1KDM4CLMNA | |
| SCHEMBL9568773 | 0.78 | ALDH1A1 (0.56) | ALDH1A1HPGDHSD11B1KDM4CPOLB | |
| SCHEMBL8947331 | 0.77 | ALDH1A1 (0.84) | ALDH1A1HPGDHSD11B1KDM4CPOLB | |
| SCHEMBL9469451 | 0.77 | ALDH1A1 (0.62) | ALDH1A1HPGDHSD11B1KDM4CPOLB | |
| SCHEMBL8947333 | 0.77 | ALDH1A1 (0.65) | ALDH1A1HPGDHSD11B1KDM4CPOLB | |
| SCHEMBL5966727 | 0.75 | ALDH1A1 (0.75) | ALDH1A1HPGDHSD11B1KDM4CPOLB | |
| SCHEMBL9689917 | 0.74 | ALDH1A1 (0.48) | ALDH1A1HPGDHSD11B1KDM4CRAB9A | |
| SCHEMBL8947275 | 0.74 | ALDH1A1 (0.61) | ALDH1A1HPGDHSD11B1KDM4CPOLB | |
| SCHEMBL8947235 | 0.73 | ALDH1A1 (0.59) | ALDH1A1HPGDHSD11B1POLBLMNA | |
| SCHEMBL8947261 | 0.72 | ALDH1A1 (0.75) | ALDH1A1HPGDHSD11B1KDM4CPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506011-A1 | Tetrazoleacetic acid derivatives having aldose reductase inhibitory activity | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1992-09-30 | — | — | EP | disclosed |