Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568919 | 0.83 | ALDH1A1 (0.39) | ALDH1A1HPGDSIGMAR1HSD11B1POLB | |
| SCHEMBL8947331 | 0.79 | ALDH1A1 (0.84) | ALDH1A1HPGDHSD11B1KDM4CPOLB | |
| SCHEMBL9469451 | 0.79 | ALDH1A1 (0.62) | ALDH1A1HPGDHSD11B1KDM4CPOLB | |
| SCHEMBL9689984 | 0.78 | ALDH1A1 (0.54) | ALDH1A1HPGDHSD11B1KDM4CPOLB | |
| SCHEMBL8947333 | 0.76 | ALDH1A1 (0.65) | ALDH1A1HPGDHSD11B1KDM4CPOLB | |
| SCHEMBL9688521 | 0.76 | SIGMAR1 (0.38) | ALDH1A1HPGDSIGMAR1POLB | |
| SCHEMBL9690598 | 0.75 | ALDH1A1 (0.53) | ALDH1A1HPGDHSD11B1KDM4CHDAC6 | |
| SCHEMBL9568778 | 0.74 | SIGMAR1 (0.38) | SIGMAR1FFAR1PPARDMRGPRX4 | |
| SCHEMBL8947261 | 0.74 | ALDH1A1 (0.75) | ALDH1A1HPGDHSD11B1KDM4CPOLB | |
| SCHEMBL5966727 | 0.74 | ALDH1A1 (0.75) | ALDH1A1HPGDHSD11B1KDM4CPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262433-A | Antidiabetic agents | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0528277-A1 | Tetrazoleacetic acid derivatives aldose reductase inhibitors | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1993-02-24 | — | — | EP | disclosed |