Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9696544 | 0.93 | ALOX15 (0.43) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL9696046 | 0.93 | ALOX15 (0.43) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL9696523 | 0.93 | MAPT (0.42) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL9696979 | 0.88 | ADRB2 (0.46) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL9696537 | 0.85 | MAPT (0.41) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL9696041 | 0.85 | MAPT (0.41) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL9695990 | 0.85 | RAB9A (0.43) | ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E | |
| SCHEMBL9696037 | 0.84 | ALOX15 (0.40) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL9694883 | 0.83 | ALOX15 (0.41) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL9696240 | 0.81 | CYP3A4 (0.43) | ALOX15ADRB2ADRA2ADRD2ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144059-A | CATECHOLAMINE ESTERS | SIMES SOCIETA ITALIANA MEDICINALI E. SINTETICI S.A. (IT) | 1992-09-01 | — | — | US | disclosed |