Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA7 | P43166 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.51 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.50 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.50 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11321047 | 0.86 | TSHR (0.56) | CYSLTR2CYSLTR1S1PR3LMNACYP3A4 | |
| SCHEMBL12972414 | 0.86 | MAPT (0.59) | SMPD1PTPN11S1PR3MEN1NR1I2 | |
| SCHEMBL28715731 | 0.85 | MAOA (0.53) | SMPD1PTPN11S1PR3MEN1NR1I2 | |
| SCHEMBL7973785 | 0.83 | HTR2A (0.51) | SMPD1PTPN11S1PR3MEN1NR1I2 | |
| SCHEMBL12567806 | 0.82 | ALDH1A1 (0.59) | PTPN11CYSLTR2CYSLTR1S1PR3MEN1 | |
| SCHEMBL30929659 | 0.81 | PTPN11 (0.69) | SMPD1PTPN11 | |
| SCHEMBL9309481 | 0.81 | LMNA (0.70) | PTPN11MEN1NR1I2LMNACHRM2 | |
| SCHEMBL9305910 | 0.81 | LMNA (0.70) | PTPN11MEN1NR1I2LMNACHRM2 | |
| SCHEMBL7954710 | 0.81 | LMNA (0.70) | PTPN11MEN1NR1I2LMNACHRM2 | |
| SCHEMBL22324528 | 0.81 | LMNA (0.70) | PTPN11MEN1NR1I2LMNACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147864-A | Bronchodilator agent, antianaphylactic agent, antishock agent, cardiotonic agent and anticarcinogenic agent | AMERICAN CYANAMID COMPANY (US) | 1992-09-15 | — | — | US | disclosed |
| US-4983592-A | Bis-arylphosphate ester antagonists of platelet activating factor | AMERICAN CYANAMID CO. (US) | 1991-01-08 | — | — | US | disclosed |
| EP-0374513-A2 | Novel bis-arylphosphate ester antagonists of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1990-06-27 | — | — | EP | disclosed |