Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | TACR3 | P29371 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.33 |
| ▸ | YAP1 | P46937 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9698341 | 0.92 | CCKBR (0.39) | TACR3TACR1CCKBR | |
| SCHEMBL9699612 | 0.92 | TACR3 (0.38) | TACR3TACR1CCKBR | |
| SCHEMBL9699592 | 0.81 | TACR3 (0.40) | ITGB3ITGA2BNPY5RTACR3TACR1 | |
| SCHEMBL7670973 | 0.80 | NPY5R (0.46) | ITGB3ITGA2BNPY5RTACR3PRKCA | |
| SCHEMBL9698370 | 0.77 | CCKBR (0.39) | CCKBR | |
| SCHEMBL9539141 | 0.75 | ITGB3 (0.46) | ITGB3ITGA2BNPY5RTACR3TACR1 | |
| SCHEMBL9700976 | 0.74 | CCKBR (0.39) | CCKBR | |
| SCHEMBL9539374 | 0.74 | TACR3 (0.45) | ITGB3ITGA2BNPY5RTACR3TACR1 | |
| SCHEMBL9699591 | 0.72 | CCKBR (0.43) | CCKBR | |
| SCHEMBL7670805 | 0.70 | TACR1 (0.44) | NPY5RTACR3TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992004025-A1 | AMINO ACID ANALOGS AS CCK ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1992-03-19 | — | — | WO | disclosed |