Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 4/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.36 |
| ▸ | YAP1 | P46937 | 3/20 | 0.35 |
| ▸ | TACR1 | P25103 | 2/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9698397 | 0.81 | ITGB3 (0.39) | TACR3ITGB3ITGA2BNPY5REPHX2 | |
| SCHEMBL7670973 | 0.81 | NPY5R (0.46) | TACR3ITGB3ITGA2BNPY5RPRKCA | |
| SCHEMBL9539141 | 0.76 | ITGB3 (0.46) | TACR3ITGB3ITGA2BNPY5RTACR1 | |
| SCHEMBL9539374 | 0.75 | TACR3 (0.45) | TACR3ITGB3ITGA2BNPY5RTACR1 | |
| SCHEMBL9699652 | 0.73 | ITGB3 (0.52) | ITGB3ITGA2BEPHX2 | |
| SCHEMBL9699654 | 0.73 | ITGB3 (0.52) | ITGB3ITGA2BEPHX2 | |
| SCHEMBL9698341 | 0.73 | CCKBR (0.39) | TACR3TACR1 | |
| SCHEMBL9699612 | 0.73 | TACR3 (0.38) | TACR3TACR1 | |
| SCHEMBL7670805 | 0.71 | TACR1 (0.44) | TACR3NPY5RTACR1 | |
| SCHEMBL7665676 | 0.70 | TACR3 (0.43) | TACR3NPY5RTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992004025-A1 | AMINO ACID ANALOGS AS CCK ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1992-03-19 | — | — | WO | disclosed |