Hypophosphorous Acid

Hypophosphorous Acid

SCHEMBL969877

O=[PH2]O.c1ccc(CCc2ccccc2)cc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.56
TDP1 Q9NUW8 3/20 0.55
KEAP1 Q14145 1/20 0.54
HDAC1 Q13547 3/20 0.50
ALDH1A1 P00352 2/20 0.50
MAOA P21397 2/20 0.50
MAOB P27338 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
HDAC2 Q92769 2/20 0.50
HDAC8 Q9BY41 2/20 0.50
HDAC6 Q9UBN7 2/20 0.50
HDAC3 O15379 1/20 0.50
MAPK1 P28482 1/20 0.50
ADRA1A P35348 1/20 0.50
HDAC4 P56524 1/20 0.50
SLC6A3 Q01959 1/20 0.50
HDAC7 Q8WUI4 1/20 0.50
HDAC10 Q969S8 1/20 0.50
HDAC11 Q96DB2 1/20 0.50
HDAC9 Q9UKV0 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenethylamine SCHEMBL9575981 0.85 HTR2A (0.73) TDP1ALDH1A1MAOAMAOBSMN1; SMN2
Hydrogen Peroxide SCHEMBL10839772 0.85 TDP1 (0.71) FFAR1TDP1KEAP1HDAC1ALDH1A1
Hydrogen Peroxide SCHEMBL10839871 0.85 TDP1 (0.71) FFAR1TDP1KEAP1HDAC1ALDH1A1
Diphenylmethane SCHEMBL11601788 0.83 CALM1 (0.67) ALDH1A1HDAC8HDAC6
Hypophosphorous Acid SCHEMBL31007063 0.82 MAOA (0.65) HDAC1MAOAMAOBSMN1; SMN2HDAC2
Benzene SCHEMBL3440179 0.82 ALDH1A1 (0.69) FFAR1TDP1KEAP1ALDH1A1MAOA
SCHEMBL62125 0.82 ALDH1A1 (0.69) FFAR1TDP1KEAP1ALDH1A1MAOA
SCHEMBL9741303 0.82 ALDH1A1 (0.69) FFAR1TDP1KEAP1ALDH1A1MAOA
Benzyl Alcohol SCHEMBL8639982 0.81 TSHR (0.74) TDP1KEAP1ALDH1A1HPGD
SCHEMBL7136305 0.79 ALDH1A1 (0.58) FFAR1TDP1KEAP1HDAC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3500544-A1 OIL-SOLUBLE PLANT MICRONUTRIENTS Huntsman Petrochemical LLC (US) 2019-06-26 EP disclosed
US-20190161418-A1 OIL-SOLUBLE PLANT MICRONUTRIENTS INDORAMA VENTURES OXIDES LLC 2019-05-30 US disclosed
CN-109563249-A The polymer blend comprising tetramethylcyclobutanediol and ethylene glycol for calendering 伊士曼化工公司 2019-04-02 CN disclosed
CN-109071371-A The soluble plant micronutrient of oil 亨斯迈石油化学有限责任公司 2018-12-21 CN disclosed
WO-2018034864-A1 OIL-SOLUBLE PLANT MICRONUTRIENTS HUNTSMAN PETROCHEMICAL LLC (US) 2018-02-22 WO disclosed
US-9822425-B2 Processes for recovering metals from aqueous solutions CYTEC TECHNOLOGY CORP. (US) 2017-11-21 US disclosed
CN-103122129-B There is the blend polymer of the notched impact strength of raising 诺瓦蒙特股份公司 2016-12-07 CN disclosed
US-20150135903-A1 PROCESSES FOR RECOVERING METALS FROM AQUEOUS SOLUTIONS CYTEC TECHNOLOGY CORP. (US) 2015-05-21 US disclosed
US-8968698-B2 Processes for recovering metals from aqueous solutions CYTEC TECHNOLOGY CORP. (US) 2015-03-03 US disclosed
US-20140127095-A1 PROCESSES FOR RECOVERING METALS FROM AQUEOUS SOLUTIONS CYTEC TECHNOLOGY CORP. (US) 2014-05-08 US disclosed
CN-103073578-A Dibenzyl phosphinic acid synthetic method UNIV TSINGHUA 2013-05-01 CN disclosed
US-8328900-B2 Processes for recovering metals from aqueous solutions CYTEC TECHNOLOGY CORP. (US) 2012-12-11 US disclosed
EP-2451985-A2 PROCESSES FOR RECOVERING METALS FROM AQUEOUS SOLUTIONS Cytec Technology Corporation (US) 2012-05-16 EP disclosed
WO-2011005736-A2 PROCESSES FOR RECOVERING METALS FROM AQUEOUS SOLUTIONS CYTEC TECHNOLOGY CORP. (US) 2011-01-13 WO disclosed
US-20110005354-A1 PROCESSES FOR RECOVERING METALS FROM AQUEOUS SOLUTIONS CYTEC TECHNOLOGY CORP. (US) 2011-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190161418-A1 OIL-SOLUBLE PLANT MICRONUTRIENTS PNPO, SLC19A1, SLC6A12 FFAR1 502/4885TDP1 2663/4885KEAP1 1714/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.