Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.57 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.54 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 4/20 | 0.49 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9697617 | 0.82 | HTR1D (0.57) | MTNR1AMTNR1B | |
| SCHEMBL9264670 | 0.82 | SNCA (0.58) | — | |
| SCHEMBL9698228 | 0.82 | ADRA2A (0.59) | — | |
| SCHEMBL8540815 | 0.82 | FAAH (0.59) | FAAHMTNR1AMTNR1BTRPV1POLB | |
| SCHEMBL9828299 | 0.80 | HTR1D (0.67) | MTNR1AMTNR1B | |
| SCHEMBL8557152 | 0.79 | MTNR1A (0.56) | MTNR1AMTNR1BPOLB | |
| SCHEMBL8537746 | 0.79 | FAAH (0.54) | FAAHMTNR1AMTNR1BTRPV1TRPM8 | |
| SCHEMBL8538858 | 0.79 | CYP1A2 (0.56) | MTNR1AMTNR1B | |
| SCHEMBL8539238 | 0.79 | FAAH (0.51) | FAAHMTNR1AMTNR1BTRPV1HTR2A | |
| SCHEMBL8540082 | 0.78 | HTR2A (0.53) | FAAHMTNR1AMTNR1BTRPV1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496222-A1 | Indole derivatives | MERCK PATENT GmbH (DE) | 1992-07-29 | — | — | EP | disclosed |