Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701321 | 0.79 | TBXA2R (0.53) | RAB9ATNFCXCL8SOS1NOD2 | |
| SCHEMBL9682976 | 0.75 | NOD1 (0.40) | RAB9ATNFCXCL8SOS1NOD2 | |
| SCHEMBL9700055 | 0.72 | TRAP1 (0.48) | MAPTPOLBTBXA2R | |
| SCHEMBL9700250 | 0.71 | CCR9 (0.41) | SMN1; SMN2LMNATBXA2RCCR9NPC1 | |
| SCHEMBL9700242 | 0.69 | TBXA2R (0.62) | SMN1; SMN2LMNADRD2TBXA2RCCR9 | |
| SCHEMBL9681953 | 0.69 | TBXA2R (0.59) | RAB9ATNFCXCL8SOS1NOD2 | |
| SCHEMBL18319794 | 0.67 | ALDH1A1 (0.47) | RAB9AALDH1A1SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL17814735 | 0.66 | PNP (0.57) | KMT2APDE4DNPC1 | |
| SCHEMBL19771396 | 0.66 | TP53 (0.51) | MAPTPOLBLMNATDP1PDE4D | |
| SCHEMBL9681986 | 0.65 | NPSR1 (0.50) | RAB9ATNFCXCL8SOS1NOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124336-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1992-06-23 | — | — | US | disclosed |