Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.62 |
| ▸ | GUSB | P08236 | 1/20 | 0.54 |
| ▸ | KIF11 | P52732 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8076297 | 0.83 | KIF11 (0.56) | DHFRGUSBKIF11ALDH1A1ALOX15 | |
| SCHEMBL28460326 | 0.81 | ALDH1A1 (0.54) | DHFRALDH1A1L3MBTL1LMNARECQL | |
| SCHEMBL28916331 | 0.80 | GUSB (0.50) | DHFRGUSBALDH1A1GAALMNA | |
| SCHEMBL62941 | 0.79 | ALDH1A1 (0.58) | DHFRGUSBALDH1A1HSD17B10GAA | |
| SCHEMBL3338050 | 0.78 | DHFR (0.52) | DHFRGUSBKIF11ALDH1A1ALOX15 | |
| SCHEMBL3344481 | 0.78 | DHFR (0.52) | DHFRGUSBKIF11ALDH1A1ALOX15 | |
| SCHEMBL29357488 | 0.77 | DHFR (0.54) | DHFRGUSBKIF11ALDH1A1GAA | |
| SCHEMBL5696233 | 0.77 | DHFR (0.54) | DHFRGUSBKIF11ALDH1A1GAA | |
| SCHEMBL11017765 | 0.77 | DDB1 (0.44) | DHFRGUSBALDH1A1GAAL3MBTL1 | |
| SCHEMBL14164082 | 0.77 | DHFR (1.00) | DHFRGUSBKIF11ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992000526-A1 | PEPTIDE SEQUENCING METHOD AND REAGENTS THEREFOR | GARIEPY KATHLEEN COX (US) | 1992-01-09 | — | — | WO | disclosed |