Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | GLA | P06280 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526437 | 0.81 | ALDH1A1 (0.45) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL9701626 | 0.81 | ALDH1A1 (0.56) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL9700723 | 0.75 | — | — | |
| SCHEMBL9701665 | 0.75 | KDM4E (0.61) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL9701832 | 0.73 | KDM4E (0.77) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL9525396 | 0.72 | ALDH1A1 (0.49) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL9525387 | 0.72 | ALDH1A1 (0.49) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL9526579 | 0.72 | KDM4E (0.56) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL9526574 | 0.72 | KDM4E (0.56) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL9524981 | 0.71 | KDM4E (0.54) | ALDH1A1KDM4EGLAGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |