Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 10/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | PDE6D | O43924 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | PDE9A | O76083 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7644788 | 0.89 | PDE5A (0.45) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL7646385 | 0.83 | PDE5A (0.44) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL7650243 | 0.80 | ALDH1A1 (0.41) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL7646365 | 0.79 | PDE5A (0.50) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL7646452 | 0.79 | ALDH1A1 (0.42) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL7576593 | 0.79 | ALDH1A1 (0.42) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL9526882 | 0.79 | ALDH1A1 (0.44) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL9702581 | 0.79 | ALDH1A1 (0.44) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL7365834 | 0.78 | FFAR4 (0.39) | ALDH1A1KDM4EGLAFFAR4PDE5A | |
| SCHEMBL7376004 | 0.78 | PDE5A (0.50) | ALDH1A1KDM4EGLAGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |