Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPN | P05981 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 5/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9492905 | 0.84 | ALOX15 (0.47) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL9168126 | 0.83 | ALOX15 (0.50) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL9701236 | 0.83 | ALOX15 (0.44) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL9701568 | 0.78 | MAPT (0.45) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL646924 | 0.78 | ALOX15 (0.63) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL9701573 | 0.77 | HPN (0.44) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL9621562 | 0.77 | ALOX15 (0.46) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL9154935 | 0.76 | ALOX15 (0.57) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL9621875 | 0.75 | VCAM1 (0.43) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL9494838 | 0.75 | MAPT (0.47) | HPNMAPTALOX15SIRT5VCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992004026-A1 | USE OF 4-HYDROXYPHENYL-THIOETHERS FOR STIMULATING SUPEROXIDE GENERATION | G.D. SEARLE & CO. (US) | 1992-03-19 | — | — | WO | disclosed |