Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11493475 | 0.98 | LOXL2 (0.41) | LOXL2HTR2ACYP2A6SMN1; SMN2TAAR1 | |
| SCHEMBL9702029 | 0.82 | TAAR1 (0.48) | TAAR1 | |
| SCHEMBL12003573 | 0.81 | CES1 (0.43) | CES2CES1AKR1B1EPHX1 | |
| SCHEMBL9700891 | 0.80 | HTR2A (0.50) | LOXL2HTR2ACYP2A6SMN1; SMN2TAAR1 | |
| SCHEMBL9701625 | 0.80 | DRD2 (0.55) | TAAR1 | |
| Hydrochloric Acid SCHEMBL9703374 | 0.79 | KEAP1 (0.48) | LOXL2HTR2ACYP2A6SMN1; SMN2TAAR1 | |
| SCHEMBL29029168 | 0.76 | MEN1 (0.39) | CES2CES1AKR1B1 | |
| SCHEMBL9701935 | 0.76 | TAAR1 (0.52) | SMN1; SMN2TAAR1 | |
| Hydrochloric Acid SCHEMBL9701893 | 0.76 | MAOA (0.50) | LOXL2HTR2ACYP2A6SMN1; SMN2TAAR1 | |
| SCHEMBL9701903 | 0.75 | TAAR1 (0.52) | TAAR1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120764-A | Administering penicillamine and allenylamines to inhibit crosslinking of collagen | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0374440-A2 | Inhibitors of lysyl oxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-27 | — | — | EP | disclosed |
| EP-0011608-A1 | Novel allenic amine and acid addition salts thereof, a process for their preparation, pharmaceutical preparations comprising them and the use of these compounds in the preparation of pharmaceutical compositions | Astra Läkemedel Aktiebolag (SE) | 1980-05-28 | — | — | EP | disclosed |