Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | DRD2 | P14416 | 3/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | DRD3 | P35462 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 3/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.53 |
| ▸ | THPO | P40225 | 3/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.53 |
| ▸ | DRD1 | P21728 | 2/20 | 0.53 |
| ▸ | DRD4 | P21917 | 2/20 | 0.53 |
| ▸ | DRD5 | P21918 | 2/20 | 0.53 |
| ▸ | APEX1 | P27695 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702029 | 0.79 | TAAR1 (0.48) | KDM4ETDP1SLC6A2ALDH1A1ADRA2A | |
| SCHEMBL10442128 | 0.76 | ACHE (0.38) | DRD2DRD1TAAR1BACE1CYP3A4 | |
| SCHEMBL9700887 | 0.74 | EGFR (0.39) | BACE1 | |
| SCHEMBL9701676 | 0.73 | KDM4E (0.56) | KDM4EMAPTMAPK1ALDH1A1TAAR1 | |
| SCHEMBL9701924 | 0.73 | LOXL2 (0.43) | TAAR1HTR2A | |
| Hydrochloric Acid SCHEMBL11493475 | 0.72 | LOXL2 (0.41) | TAAR1HTR2A | |
| Dopamine SCHEMBL1059422 | 0.71 | KDM4E (0.91) | KDM4EMAPTALOX15TDP1DRD2 | |
| SCHEMBL9701911 | 0.70 | TAAR1 (0.35) | KDM4EMAPTALOX15TDP1RECQL | |
| SCHEMBL9701941 | 0.70 | TYR (0.47) | MAPTALOX15TDP1TP53TSHR | |
| SCHEMBL9701935 | 0.70 | TAAR1 (0.52) | KDM4EALOX15ALDH1A1TP53CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120764-A | Administering penicillamine and allenylamines to inhibit crosslinking of collagen | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0374440-A2 | Inhibitors of lysyl oxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-27 | — | — | EP | disclosed |