Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701649 | 0.85 | CTSD (0.49) | NPC1HPGDALDH1A1GAAHTT | |
| SCHEMBL9703267 | 0.80 | CA12 (0.44) | HPGDALDH1A1GAAHSD17B10SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4670042 | 0.74 | RAB9A (0.52) | KMT2AMEN1NPC1RAB9AHPGD | |
| SCHEMBL11110232 | 0.73 | KMT2A (0.49) | KMT2AMEN1NPC1RAB9AHPGD | |
| SCHEMBL7441345 | 0.73 | KMT2A (0.45) | KMT2AMEN1NPC1RAB9AHPGD | |
| SCHEMBL9702788 | 0.73 | TAAR1 (0.42) | KMT2AMEN1POLBALDH1A1GAA | |
| SCHEMBL9701879 | 0.72 | MAPT (0.47) | KMT2AMEN1HPGDPOLBALDH1A1 | |
| SCHEMBL9702039 | 0.72 | SMN1; SMN2 (0.47) | KMT2AMEN1L3MBTL1POLBALDH1A1 | |
| SCHEMBL9701621 | 0.72 | ALDH1A1 (0.57) | KMT2AMEN1NPC1RAB9AHPGD | |
| SCHEMBL3863254 | 0.72 | KMT2A (0.58) | KMT2AMEN1NPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120764-A | Administering penicillamine and allenylamines to inhibit crosslinking of collagen | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0374440-A2 | Inhibitors of lysyl oxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-27 | — | — | EP | disclosed |