Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.46 |
| ▸ | CA7 | P43166 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 3/20 | 0.43 |
| ▸ | MMP7 | P09237 | 3/20 | 0.43 |
| ▸ | MMP12 | P39900 | 3/20 | 0.43 |
| ▸ | MMP13 | P45452 | 3/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26597085 | 0.82 | AKT1 (0.43) | CA12CA7CA9CA14SMN1; SMN2 | |
| SCHEMBL10476922 | 0.81 | MMP13 (0.46) | SMN1; SMN2MMP1MMP7MMP12MMP13 | |
| SCHEMBL26597086 | 0.77 | CNR2 (0.47) | MAPTGAAMMP1MMP13ALDH1A1 | |
| SCHEMBL28773565 | 0.75 | MMP1 (0.47) | SMN1; SMN2MAPTMMP1MMP7MMP12 | |
| SCHEMBL10012441 | 0.75 | CA12 (0.44) | CA12CA7CA9CA14SMN1; SMN2 | |
| SCHEMBL28101227 | 0.75 | MAPT (0.59) | SMN1; SMN2MAPTMMP1LMNA | |
| SCHEMBL27853852 | 0.74 | ALDH1A1 (0.44) | CA12CA9SMN1; SMN2MAPTMMP1 | |
| SCHEMBL28970084 | 0.74 | MTNR1A (0.53) | CA12CA7CA9CA14ALDH1A1 | |
| SCHEMBL6095644 | 0.73 | LMNA (0.47) | CA12CA7CA9CA14SMN1; SMN2 | |
| SCHEMBL25384618 | 0.72 | SMN1; SMN2 (0.53) | CA12CA7CA9CA14SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175338-A | Anticoagulants, vasodilation, antilipemic agents | TEIJIN LIMITED (JP) | 1992-12-29 | — | — | US | disclosed |
| EP-0247740-B1 | NOVEL ISOCARBACYCLINS AND PROCESSES FOR PRODUCTION THEREOF | TEIJIN LIMITED (JP) | 1990-09-26 | — | — | EP | disclosed |
| US-4788319-A | PROSTAGLANDIN INTERMEDIATES | TEIJIN LIMITED (JP) | 1988-11-29 | — | — | US | disclosed |
| EP-0247740-A2 | Novel isocarbacyclins and processes for production thereof | TEIJIN LIMITED (JP) | 1987-12-02 | — | — | EP | disclosed |