Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.56 |
| ▸ | DRD3 | P35462 | 2/20 | 0.56 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703843 | 0.86 | DRD2 (0.52) | DRD2DRD3DRD4 | |
| SCHEMBL9705545 | 0.86 | DRD2 (0.64) | DRD2DRD3DRD4 | |
| SCHEMBL4483845 | 0.76 | DRD2 (0.64) | DRD2DRD3DRD4 | |
| SCHEMBL9773137 | 0.76 | DRD2 (0.64) | DRD2DRD3DRD4 | |
| SCHEMBL4483728 | 0.75 | DRD2 (0.62) | DRD2DRD3DRD4 | |
| SCHEMBL7700873 | 0.74 | ADRA1D (0.65) | DRD2DRD3DRD4 | |
| SCHEMBL9703330 | 0.74 | DRD2 (0.81) | DRD2DRD3DRD4 | |
| SCHEMBL9874332 | 0.74 | DRD2 (0.61) | DRD2DRD3DRD4 | |
| SCHEMBL10749274 | 0.73 | DRD2 (0.48) | DRD2DRD3DRD4 | |
| SCHEMBL10855215 | 0.73 | DRD2 (0.52) | DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992012977-A1 | SUBSTITUTED INDOLES AS CENTRAL NERVOUS SYSTEM AGENTS | WARNER-LAMBERT COMPANY (US) | 1992-08-06 | — | — | WO | claimed |
| WO-1992012977-A1 | SUBSTITUTED INDOLES AS CENTRAL NERVOUS SYSTEM AGENTS | WARNER-LAMBERT COMPANY (US) | 1992-08-06 | — | — | WO | disclosed |
| US-5124332-A | Dopaminergic agents, hypotensive agents | WARNER-LAMBERT COMPANY (US) | 1992-06-23 | — | — | US | disclosed |