Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | APAF1 | O14727 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 4/20 | 0.49 |
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
| ▸ | CA2 | P00918 | 4/20 | 0.49 |
| ▸ | CA9 | Q16790 | 4/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.49 |
| ▸ | BRD4 | O60885 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | UBE2N | P61088 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504689 | 0.78 | ALDH1A1 (0.47) | MAPTKDM4EALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL5604939 | 0.77 | CA1 (0.71) | ALDH1A1NPSR1CA12CA1CA2 | |
| SCHEMBL9720960 | 0.74 | L3MBTL1 (0.70) | MAPTKDM4EALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL5309421 | 0.73 | ALDH1A1 (1.00) | MAPTKDM4EALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL9290377 | 0.73 | CYP1B1 (0.59) | MAPTKDM4EALDH1A1SMN1; SMN2NPSR1 | |
| Hydrochloric Acid SCHEMBL9080389 | 0.72 | ALDH1A1 (0.97) | MAPTKDM4EALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL28277899 | 0.72 | CYP1B1 (0.67) | MAPTKDM4EALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL9702392 | 0.71 | MAPT (0.79) | MAPTKDM4EALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL9290437 | 0.71 | KMT2A (0.56) | MAPTKDM4EALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL9290283 | 0.70 | NPSR1 (0.52) | MAPTKDM4EALDH1A1SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992005153-A1 | ANTIPROLIFERATIVE SUBSTITUTED NAPHTHALENE COMPOUNDS | AGOURON PHARMACEUTICALS, INC. (US) | 1992-04-02 | — | — | WO | disclosed |