Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3099432 | 0.79 | NOTUM (0.49) | NOTUMMEN1KMT2AEGFRABCG2 | |
| SCHEMBL9710552 | 0.70 | ADH5 (0.52) | MEN1KMT2ACYP3A4 | |
| SCHEMBL11199895 | 0.70 | MAP2K1 (0.49) | MEN1KMT2ATGFBR1MAP2K1KDM4E | |
| SCHEMBL6538871 | 0.69 | MAOB (0.47) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10994404 | 0.66 | PARP1 (0.45) | MEN1KMT2ATGFBR1KDM4ENPC1 | |
| SCHEMBL17260662 | 0.66 | PDE3B (0.63) | NOTUMMEN1KMT2AEGFRKDM4E | |
| SCHEMBL17260649 | 0.66 | PDE3B (0.63) | NOTUMMEN1KMT2AEGFRKDM4E | |
| SCHEMBL8846 | 0.66 | PDE3B (0.46) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6603063 | 0.65 | MAP2K1 (0.54) | NOTUMMEN1KMT2AEGFRMAP2K1 | |
| SCHEMBL9201010 | 0.65 | MEN1 (0.61) | MEN1KMT2AESR1ESR2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0223177-B1 | CARDIOTONIC PHENYL OXAZOLONES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-08-19 | — | — | EP | disclosed |