SCHEMBL9706678

SCHEMBL9706678

Cn1c2c(c(=O)n(-c3cc(C(=O)O)c(Br)cc3Cl)c1=O)CCC2

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CMA1 P23946 1/20 0.34
RXFP1 Q9HBX9 1/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
GAA P10253 1/20 0.31
LCK P06239 1/20 0.30
FYN P06241 1/20 0.30
NOTUM Q6P988 2/20 0.30
GRM4 Q14833 2/20 0.30
KDM4E B2RXH2 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9706680 0.90 LMNA (0.37) CMA1RXFP1GAANOTUMGRM4
SCHEMBL9706623 0.87 TTR (0.32) CMA1RXFP1SMN1; SMN2GAALCK
SCHEMBL9706485 0.86 SLC6A2 (0.34)
SCHEMBL9706554 0.82 HPGD (0.34) CMA1RXFP1SMN1; SMN2GAANOTUM
SCHEMBL10645585 0.81 HPGD (0.34) CMA1RXFP1SMN1; SMN2GAANOTUM
SCHEMBL9706687 0.80 HPGD (0.34) CMA1RXFP1SMN1; SMN2
SCHEMBL10873317 0.78 RXRA (0.34) CMA1RXFP1GAANOTUM
SCHEMBL9706672 0.78 SLC6A2 (0.35) SMN1; SMN2KDM4EHSD17B10
SCHEMBL9706570 0.77 TDP1 (0.50) CMA1SMN1; SMN2NOTUMKDM4E
SCHEMBL10645580 0.76 HPGD (0.31) RXFP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0195346-B1 3-ARYL URACILES AND THEIR USE AS HERBICIDES CIBA-GEIGY AG (CH) 1992-06-24 EP claimed