Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CMA1 | P23946 | 3/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10645585 | 0.99 | HPGD (0.34) | HPGDSMN1; SMN2CMA1EPHX2MEN1 | |
| SCHEMBL9706687 | 0.98 | HPGD (0.34) | HPGDSMN1; SMN2CMA1EPHX2MEN1 | |
| SCHEMBL9423141 | 0.91 | TSHR (0.36) | HPGDSMN1; SMN2ALDH1A1TSHRMAPT | |
| SCHEMBL10873317 | 0.90 | RXRA (0.34) | CMA1MEN1LMNAKMT2ATTR | |
| SCHEMBL9706680 | 0.90 | LMNA (0.37) | CMA1MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL10645580 | 0.89 | HPGD (0.31) | HPGDSMN1; SMN2TSHRMAPTRXFP1 | |
| SCHEMBL9706633 | 0.88 | HPGD (0.34) | HPGDSMN1; SMN2MEN1ALDH1A1LMNA | |
| SCHEMBL9706682 | 0.87 | TSHR (0.33) | HPGDSMN1; SMN2EPHX2MEN1ALDH1A1 | |
| SCHEMBL9706623 | 0.87 | TTR (0.32) | SMN1; SMN2CMA1TTRRXFP1GAA | |
| SCHEMBL9706651 | 0.86 | PPOX (0.34) | HPGDSMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0195346-B1 | 3-ARYL URACILES AND THEIR USE AS HERBICIDES | CIBA-GEIGY AG (CH) | 1992-06-24 | — | — | EP | claimed |
| EP-0195346-B1 | 3-ARYL URACILES AND THEIR USE AS HERBICIDES | CIBA-GEIGY AG (CH) | 1992-06-24 | — | — | EP | disclosed |
| US-4760163-A | 3-(5-carboxy-4-substituted-phenyl)-(thio)uracil-esters and salts | HOFFMANN-LAROCHE INC. (US) | 1988-07-26 | — | — | US | disclosed |
| US-4746352-A | HERBICIDES | HOFFMANN-LA ROCHE INC. (US) | 1988-05-24 | — | — | US | disclosed |
| EP-0195346-A2 | 3-Aryl uraciles and their use as herbicides | CIBA-GEIGY AG (CH) | 1986-09-24 | — | — | EP | disclosed |