Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | GPR18 | Q14330 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9707888 | 0.95 | ADORA3 (0.41) | ADORA3ADORA2AADORA1 | |
| SCHEMBL9707710 | 0.92 | MAPT (0.39) | HPGDLMNASMN1; SMN2 | |
| SCHEMBL9708256 | 0.88 | HPGD (0.44) | HPGDADORA3ADORA2A | |
| SCHEMBL9707666 | 0.88 | ADORA3 (0.42) | ADORA3ADORA2AADORA1 | |
| SCHEMBL9707689 | 0.88 | TRPC5 (0.45) | ADORA3 | |
| SCHEMBL9707817 | 0.86 | AGTR1 (0.44) | HPGDAGTR1AGTR2LMNA | |
| SCHEMBL9707374 | 0.85 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL9707814 | 0.85 | ADORA3 (0.42) | HPGDADORA3AGTR1AGTR2LMNA | |
| SCHEMBL9707771 | 0.84 | ALDH1A1 (0.45) | AGTR1AGTR2LMNASMN1; SMN2 | |
| SCHEMBL9707907 | 0.84 | GPR18 (0.37) | HPGDAGTR1AGTR2GPR18 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007852-A1 | BIPHENYLALKYL XANTHINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1992-05-14 | — | — | WO | claimed |
| WO-1992007852-A1 | BIPHENYLALKYL XANTHINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1992-05-14 | — | — | WO | disclosed |