Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709660 | 0.86 | AGTR1 (0.45) | AGTR1AGTR2ALDH1A1L3MBTL1RAB9A | |
| SCHEMBL9709740 | 0.85 | LTB4R2 (0.51) | AGTR1AGTR2PPARG | |
| SCHEMBL9709698 | 0.84 | AGTR1 (0.50) | AGTR1AGTR2 | |
| SCHEMBL9709700 | 0.81 | VCP (0.52) | AGTR1AGTR2ALDH1A1L3MBTL1PPARG | |
| SCHEMBL9709814 | 0.79 | CD38 (0.55) | ALDH1A1L3MBTL1PPARG | |
| SCHEMBL9709741 | 0.78 | KDM4E (0.57) | AGTR1AGTR2PPARG | |
| SCHEMBL9709750 | 0.78 | DHODH (0.59) | AGTR1AGTR2PPARG | |
| SCHEMBL9709862 | 0.77 | BDKRB1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL3058636 | 0.75 | CD38 (0.56) | RAB9A | |
| SCHEMBL9709729 | 0.74 | AGTR1 (0.44) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | claimed |
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | disclosed |