Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.51 |
| ▸ | ACP1 | P24666 | 3/20 | 0.50 |
| ▸ | DHODH | Q02127 | 1/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.50 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.48 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709741 | 0.93 | KDM4E (0.57) | LTB4R2ACP1DHODHAGTR1AGTR2 | |
| SCHEMBL9709750 | 0.92 | DHODH (0.59) | LTB4R2DHODHAGTR1AGTR2KDM4E | |
| SCHEMBL9709862 | 0.87 | BDKRB1 (0.46) | LTB4R2DHODHAGTR1AGTR2 | |
| SCHEMBL3058636 | 0.87 | CD38 (0.56) | LTB4R2ACP1PDE7APDE7B | |
| Hydrochloric Acid SCHEMBL9494706 | 0.86 | CD38 (0.55) | LTB4R2ACP1PDE7APDE7B | |
| SCHEMBL9709723 | 0.85 | AGTR1 (0.47) | AGTR1AGTR2PPARG | |
| SCHEMBL9709660 | 0.81 | AGTR1 (0.45) | LTB4R2AGTR1AGTR2 | |
| SCHEMBL9709569 | 0.80 | PPARG (0.48) | LTB4R2AGTR1AGTR2KDM4EPPARG | |
| SCHEMBL9177090 | 0.79 | AGTR1 (0.63) | AGTR1AGTR2 | |
| SCHEMBL9494718 | 0.78 | ACP1 (0.54) | ACP1AGTR1AGTR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | claimed |