Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 2/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.42 |
| ▸ | BRS3 | P32247 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709569 | 0.85 | PPARG (0.48) | PLK1AGTR1AGTR2BRS3KDM4E | |
| SCHEMBL9709862 | 0.82 | BDKRB1 (0.46) | DHODHAGTR1AGTR2BDKRB1 | |
| SCHEMBL9709750 | 0.79 | DHODH (0.59) | DHODHPLK1AGTR1AGTR2BRS3 | |
| SCHEMBL9709925 | 0.77 | PDE4A (0.42) | AGTR1AGTR2 | |
| SCHEMBL3737185 | 0.75 | FOLH1 (0.63) | DHODHAGTR1AGTR2BRS3FOLH1 | |
| SCHEMBL9709947 | 0.75 | AGTR1 (0.40) | AGTR1AGTR2BDKRB1 | |
| SCHEMBL9709741 | 0.74 | KDM4E (0.57) | DHODHPLK1AGTR1AGTR2BRS3 | |
| SCHEMBL9709803 | 0.71 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL9709740 | 0.71 | LTB4R2 (0.51) | DHODHAGTR1AGTR2KDM4E | |
| SCHEMBL7780583 | 0.71 | KAT8 (0.65) | PLK1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | claimed |