SCHEMBL9710233

SCHEMBL9710233

ON=C(ON=Cc1ccccc1)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G7 Q13093 6/20 0.61
MIF P14174 1/20 0.50
RAB9A P51151 4/20 0.40
NPC1 O15118 3/20 0.40
GRIN2D O15399 2/20 0.40
GRIN3B O60391 2/20 0.40
GRIN1 Q05586 2/20 0.40
GRIN2A Q12879 2/20 0.40
GRIN2B Q13224 2/20 0.40
GRIN2C Q14957 2/20 0.40
GRIN3A Q8TCU5 2/20 0.40
FAAH O00519 2/20 0.40
LMNA P02545 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
TAAR1 Q96RJ0 1/20 0.40
MAPT P10636 3/20 0.39
KMT2A Q03164 1/20 0.39
ALOX15 P16050 1/20 0.39
NFKB1 P19838 1/20 0.38
NFKB2 Q00653 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3222745 0.76 PLA2G7 (1.00) PLA2G7MIFRAB9ANPC1FAAH
SCHEMBL3222751 0.76 PLA2G7 (1.00) PLA2G7MIFRAB9ANPC1FAAH
SCHEMBL9709937 0.73 LMNA (0.57) PLA2G7MIFRAB9ANPC1GRIN2D
SCHEMBL6420965 0.72 PLA2G7 (0.69) PLA2G7MIFRAB9ANPC1FAAH
SCHEMBL10332554 0.71 PLA2G7 (0.67) PLA2G7MIFRAB9ANPC1GRIN2D
SCHEMBL674618 0.71 GAA (0.41) LMNAL3MBTL1MAPTKMT2A
SCHEMBL13930605 0.70 PLA2G7 (0.87) PLA2G7MIFRAB9ANPC1LMNA
SCHEMBL213322 0.69 PLA2G7 (0.65) PLA2G7MIFRAB9ANPC1FAAH
SCHEMBL213321 0.69 PLA2G7 (0.65) PLA2G7MIFRAB9ANPC1FAAH
SCHEMBL8530447 0.67 TSHR (0.48) RAB9ALMNAL3MBTL1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105130843-B Benzyl hydrazone compounds and preparation method and application 中国农业大学 2017-08-04 CN disclosed
CN-103922904-B A kind of method of synthetic 2-fluorinated aryl carbonyls JIANG University OF TECHNOLOGY (CN) 2016-05-18 CN disclosed
CN-105130843-A Benzyl hydrazone compound and preparation method and uses thereof UNIV CHINA AGRICULTURAL 2015-12-09 CN disclosed
CN-103922904-A Method for synthesizing 2-fluoroarylcarbonyl compounds UNIV ZHEJIANG TECHNOLOGY 2014-07-16 CN disclosed
CN-101648887-B Method for synthesizing o-trans-(3-Cl-2-propenyl) hydroxylamine hydrochloride NINGBO OCEAN CHEMICAL NEW MATERIAL TECHNOLOGY CO LTD 2012-08-15 CN disclosed
CN-101648887-A Method for synthesizing o-trans-(3-Cl-2-propenyl) hydroxylamine hydrochloride NINGBO OCEAN CHEMICAL NEW MATE 2010-02-17 CN disclosed
EP-0479055-A1 Benzaldoximether derivatives BASF Aktiengesellschaft (DE) 1992-04-08 EP disclosed