Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | LDHB | P07195 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711543 | 0.87 | LDHA (0.44) | LDHALDHBP2RX7ALDH1A1RAB9A | |
| SCHEMBL9711615 | 0.86 | LDHA (0.42) | LDHALDHBKMT2AALDH1A1MEN1 | |
| SCHEMBL9711657 | 0.86 | MRGPRX4 (0.42) | LDHALDHBKMT2AALDH1A1MEN1 | |
| SCHEMBL9711591 | 0.84 | MAPT (0.39) | LDHAP2RX7KMT2A | |
| SCHEMBL9711624 | 0.82 | LDHA (0.41) | LDHALDHBP2RX7KMT2AALDH1A1 | |
| SCHEMBL9711500 | 0.81 | HSD11B1 (0.41) | LDHAHSD11B1ALDH1A1NPC1RAB9A | |
| SCHEMBL9711629 | 0.81 | ALDH1A1 (0.38) | LDHAHSD11B1LDHBKMT2AALDH1A1 | |
| SCHEMBL9711476 | 0.79 | LDHA (0.44) | LDHALDHBKMT2AALDH1A1MEN1 | |
| SCHEMBL9711698 | 0.78 | KMO (0.43) | LDHALDHB | |
| SCHEMBL9711509 | 0.76 | HPGD (0.43) | HPGDKMT2AALDH1A1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114461-A | Herbicides | MAY & BAKER LIMITED (GB) | 1992-05-19 | — | — | US | disclosed |
| EP-0278742-A2 | Cyclic diones | MAY & BAKER LIMITED (GB) | 1988-08-17 | — | — | EP | disclosed |