Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | HPD | P32754 | 1/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.37 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 3/20 | 0.37 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.36 |
| ▸ | LDHB | P07195 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAT2A | P31153 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711752 | 0.88 | CES2 (0.43) | MRGPRX4HPDAVPR2GPR27HDAC11 | |
| SCHEMBL9711547 | 0.86 | LDHA (0.41) | LDHALDHBLMNAMEN1ALDH1A1 | |
| SCHEMBL9711543 | 0.84 | LDHA (0.44) | LDHALDHBSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL9711506 | 0.84 | HPD (0.61) | HPDMAPTHTTLMNAMEN1 | |
| SCHEMBL9711615 | 0.83 | LDHA (0.42) | LDHALDHBSMN1; SMN2LMNAMEN1 | |
| SCHEMBL9711548 | 0.82 | HDAC11 (0.43) | HDAC11PARP1PARP2 | |
| SCHEMBL9711648 | 0.81 | CES2 (0.43) | MAPTSMN1; SMN2HTTLMNAMEN1 | |
| SCHEMBL9711624 | 0.80 | LDHA (0.41) | LDHALDHBSMN1; SMN2LMNAMEN1 | |
| SCHEMBL9711749 | 0.80 | LMNA (0.38) | HDAC11MAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL9711591 | 0.80 | MAPT (0.39) | LDHAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114461-A | Herbicides | MAY & BAKER LIMITED (GB) | 1992-05-19 | — | — | US | disclosed |
| EP-0278742-A2 | Cyclic diones | MAY & BAKER LIMITED (GB) | 1988-08-17 | — | — | EP | disclosed |