SCHEMBL9711698

SCHEMBL9711698

O=C1CC(c2ccccc2)NC(=O)C1C(=O)c1ccc(Cl)c(Cl)c1

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMO O15229 2/20 0.43
LDHA P00338 3/20 0.41
PYGL P06737 2/20 0.41
PYGM P11217 2/20 0.41
LDHB P07195 1/20 0.40
SLC6A2 P23975 1/20 0.39
SLC6A3 Q01959 1/20 0.39
TSHR P16473 1/20 0.39
PGR P06401 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9711523 0.85 SLC6A3 (0.40) LDHALDHBSLC6A3
SCHEMBL9711454 0.84 MAPT (0.44) LDHALDHB
SCHEMBL9711615 0.84 LDHA (0.42) LDHALDHBSLC6A2SLC6A3
SCHEMBL9711476 0.82 LDHA (0.44) LDHALDHBSLC6A3
SCHEMBL9711543 0.82 LDHA (0.44) LDHALDHBSLC6A3
SCHEMBL9711500 0.81 HSD11B1 (0.41) LDHA
SCHEMBL9711520 0.81 SMN1; SMN2 (0.37) LDHALDHBTSHR
SCHEMBL9711470 0.81 EPHX1 (0.43)
SCHEMBL9711528 0.81 F2RL1 (0.42)
SCHEMBL9711624 0.81 LDHA (0.41) LDHALDHBSLC6A2SLC6A3TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5114461-A Herbicides MAY & BAKER LIMITED (GB) 1992-05-19 US disclosed