Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 5/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | HPD | P32754 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | FLT4 | P35916 | 1/20 | 0.35 |
| ▸ | ABL2 | P42684 | 1/20 | 0.35 |
| ▸ | BLK | P51451 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711573 | 0.87 | CES2 (0.50) | KMT2AHPDCRBNFLT4PARP1 | |
| SCHEMBL9711769 | 0.83 | MEN1 (0.43) | KMT2AMEN1CYP1A2 | |
| SCHEMBL9711566 | 0.78 | KMT2A (0.38) | KMT2AATMHCRTR1HCRTR2CRBN | |
| SCHEMBL9711660 | 0.78 | HPD (0.51) | ATMHPDPARP1PARP10 | |
| SCHEMBL9711517 | 0.76 | HPD (0.46) | KMT2AHPDPARP1PARP10CES2 | |
| SCHEMBL9711591 | 0.76 | MAPT (0.39) | KMT2AATMAURKAHCRTR1HCRTR2 | |
| SCHEMBL16832049 | 0.73 | L3MBTL1 (0.44) | KMT2AATMHCRTR1HCRTR2P2RX7 | |
| SCHEMBL9711453 | 0.72 | HPD (0.73) | KMT2AHPDFLT4MEN1CYP1A2 | |
| SCHEMBL9711471 | 0.71 | CES2 (0.43) | KMT2AHPDCRBNPARP1PARP10 | |
| SCHEMBL9711702 | 0.71 | BACE1 (0.49) | KMT2AHPDPARP1PARP10CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114461-A | Herbicides | MAY & BAKER LIMITED (GB) | 1992-05-19 | — | — | US | disclosed |
| EP-0278742-A2 | Cyclic diones | MAY & BAKER LIMITED (GB) | 1988-08-17 | — | — | EP | disclosed |