Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | LDHB | P07195 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TPMT | P51580 | 1/20 | 0.34 |
| ▸ | CTRC | Q99895 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711454 | 0.90 | MAPT (0.44) | SMN1; SMN2LDHAMAPTALOX15HTT | |
| SCHEMBL9711500 | 0.87 | HSD11B1 (0.41) | SMN1; SMN2LDHAMAPTALDH1A1HTR2A | |
| SCHEMBL9711645 | 0.84 | MEN1 (0.44) | SMN1; SMN2LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL9711548 | 0.84 | HDAC11 (0.43) | SIGMAR1 | |
| SCHEMBL9711577 | 0.82 | SMN1; SMN2 (0.37) | SMN1; SMN2LDHALDHBLMNAMEN1 | |
| SCHEMBL9711698 | 0.81 | KMO (0.43) | LDHALDHBTSHR | |
| SCHEMBL9711470 | 0.79 | EPHX1 (0.43) | SMN1; SMN2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9711523 | 0.79 | SLC6A3 (0.40) | LDHALDHBMEN1KMT2AALDH1A1 | |
| SCHEMBL9711528 | 0.79 | F2RL1 (0.42) | SMN1; SMN2MAPTHTTLMNAMEN1 | |
| SCHEMBL9711543 | 0.77 | LDHA (0.44) | SMN1; SMN2LDHALDHBLMNABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114461-A | Herbicides | MAY & BAKER LIMITED (GB) | 1992-05-19 | — | — | US | disclosed |
| EP-0278742-A2 | Cyclic diones | MAY & BAKER LIMITED (GB) | 1988-08-17 | — | — | EP | disclosed |