Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL1 | P55085 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711454 | 0.87 | MAPT (0.44) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL9711523 | 0.85 | SLC6A3 (0.40) | KMT2AMEN1ALDH1A1PARP1NPSR1 | |
| SCHEMBL9711470 | 0.85 | EPHX1 (0.43) | KMT2AMEN1MAPTALDH1A1NPC1 | |
| SCHEMBL9711533 | 0.82 | NPC1 (0.43) | KMT2ALMNAHTTALDH1A1NPC1 | |
| SCHEMBL9711648 | 0.82 | CES2 (0.43) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL9711582 | 0.81 | LMNA (0.49) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL9711698 | 0.81 | KMO (0.43) | — | |
| SCHEMBL9711474 | 0.80 | HSD11B1 (0.42) | — | |
| SCHEMBL9711500 | 0.79 | HSD11B1 (0.41) | HTR2AMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL9711520 | 0.79 | SMN1; SMN2 (0.37) | HTR2AKMT2AMEN1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114461-A | Herbicides | MAY & BAKER LIMITED (GB) | 1992-05-19 | — | — | US | disclosed |
| EP-0278742-A2 | Cyclic diones | MAY & BAKER LIMITED (GB) | 1988-08-17 | — | — | EP | disclosed |