Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711752 | 0.88 | CES2 (0.43) | LMNAMAPTHDAC11SMN1; SMN2ALDH1A1 | |
| SCHEMBL9711591 | 0.88 | MAPT (0.39) | MAPT | |
| SCHEMBL9711629 | 0.84 | ALDH1A1 (0.38) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9711658 | 0.82 | HSD11B1 (0.40) | MGLL | |
| SCHEMBL9711543 | 0.82 | LDHA (0.44) | LMNASLC6A3SMN1; SMN2ALDH1A1 | |
| SCHEMBL9711557 | 0.81 | ALDH1A1 (0.39) | LMNAMGLLSMN1; SMN2ALDH1A1 | |
| SCHEMBL9711577 | 0.81 | SMN1; SMN2 (0.37) | LMNAMGLLSMN1; SMN2ALDH1A1 | |
| SCHEMBL9711646 | 0.81 | ITGB1 (0.42) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9711548 | 0.81 | HDAC11 (0.43) | MGLLHDAC11 | |
| SCHEMBL9711657 | 0.80 | MRGPRX4 (0.42) | LMNAMAPTHDAC11SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114461-A | Herbicides | MAY & BAKER LIMITED (GB) | 1992-05-19 | — | — | US | disclosed |
| EP-0278742-A2 | Cyclic diones | MAY & BAKER LIMITED (GB) | 1988-08-17 | — | — | EP | disclosed |