Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711595 | 0.87 | HCRTR1 (0.40) | LDHAMAPTTSHRHTT | |
| SCHEMBL9711658 | 0.85 | HSD11B1 (0.40) | LDHA | |
| SCHEMBL9711646 | 0.84 | ITGB1 (0.42) | LDHASMN1; SMN2ALDH1A1 | |
| SCHEMBL9711543 | 0.82 | LDHA (0.44) | LDHARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9711629 | 0.81 | ALDH1A1 (0.38) | LDHASMN1; SMN2ALDH1A1 | |
| SCHEMBL9711557 | 0.81 | ALDH1A1 (0.39) | LDHASMN1; SMN2ALDH1A1 | |
| SCHEMBL9711577 | 0.81 | SMN1; SMN2 (0.37) | LDHASMN1; SMN2ALDH1A1 | |
| SCHEMBL6607989 | 0.79 | LDHA (0.43) | LDHAPOLBSMN1; SMN2TSHR | |
| SCHEMBL9711454 | 0.79 | MAPT (0.44) | LDHASMN1; SMN2ALDH1A1MAPTHTT | |
| SCHEMBL9711749 | 0.78 | LMNA (0.38) | SMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114461-A | Herbicides | MAY & BAKER LIMITED (GB) | 1992-05-19 | — | — | US | disclosed |
| EP-0278742-A2 | Cyclic diones | MAY & BAKER LIMITED (GB) | 1988-08-17 | — | — | EP | disclosed |