Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CTSS | P25774 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9712750 | 0.82 | CA2 (0.34) | CA2TSHRALDH1A1TDP1ELANE | |
| SCHEMBL1148444 | 0.79 | ALDH1A1 (0.50) | CA2TSHRALDH1A1TDP1ELANE | |
| SCHEMBL9712669 | 0.78 | NPSR1 (0.35) | CA2TSHRALDH1A1TDP1ELANE | |
| SCHEMBL30663932 | 0.77 | ALDH1A1 (0.48) | CA2TSHRALDH1A1TDP1ELANE | |
| SCHEMBL1812262 | 0.76 | AKR1C3 (0.48) | PDK1PDK2PDK3PDK4TSHR | |
| SCHEMBL9066557 | 0.76 | CES2 (0.50) | ALDH1A1POLBTP53GAAHTT | |
| SCHEMBL9712498 | 0.74 | POLB (0.38) | TSHRALDH1A1TDP1ELANERBP4 | |
| SCHEMBL9712528 | 0.73 | AKR1C3 (0.50) | ALDH1A1TDP1MAPTSMN1; SMN2GAA | |
| SCHEMBL9712354 | 0.73 | ALDH1A1 (0.42) | CA2TSHRALDH1A1TDP1ELANE | |
| SCHEMBL9066561 | 0.72 | PDK1 (0.52) | PDK1PDK2PDK3PDK4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5117057-A | Insecticidal N' substituted-N-N'-disubstituted-hydrazines | ROHM AND HAAS COMPANY (US) | 1992-05-26 | — | — | US | disclosed |