Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10502745 | 0.84 | L3MBTL1 (0.46) | L3MBTL1MAPK1KMT2ALMNAMEN1 | |
| SCHEMBL9713703 | 0.81 | ABCB11 (0.51) | L3MBTL1MAPK1KMT2ALMNAMEN1 | |
| SCHEMBL9713437 | 0.81 | PDE7A (0.40) | L3MBTL1MAPK1KMT2ALMNAMEN1 | |
| SCHEMBL9713650 | 0.79 | SMN1; SMN2 (0.41) | L3MBTL1KMT2ALMNASMN1; SMN2TP53 | |
| SCHEMBL30226615 | 0.79 | PDE7A (0.39) | L3MBTL1MAPK1KMT2ALMNAMEN1 | |
| SCHEMBL9643164 | 0.75 | ABCB11 (0.62) | L3MBTL1MAPK1LMNASMN1; SMN2TP53 | |
| SCHEMBL30226594 | 0.75 | ABCB11 (0.43) | L3MBTL1MAPK1KMT2ALMNAMEN1 | |
| SCHEMBL9643180 | 0.74 | CHRM1 (0.49) | L3MBTL1KMT2ALMNAMEN1SMN1; SMN2 | |
| SCHEMBL9642749 | 0.71 | ABCB11 (0.53) | L3MBTL1MAPK1LMNASMN1; SMN2TP53 | |
| SCHEMBL9643350 | 0.70 | UCHL1 (0.41) | L3MBTL1MAPK1LMNASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |