1,2-Dichlorobenzene

1,2-Dichlorobenzene

SCHEMBL9713897

CCOC(C)=O.Clc1ccccc1Cl

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.58
LMNA P02545 2/20 0.58
HSD17B10 Q99714 2/20 0.58
TSHR P16473 3/20 0.50
CASP1 P29466 1/20 0.49
NLRP3 Q96P20 1/20 0.46
MAPT P10636 2/20 0.44
PDE4B Q07343 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
CYP1A2 P05177 2/20 0.43
CYP3A4 P08684 2/20 0.43
CYP2C9 P11712 2/20 0.43
CYP2C19 P33261 2/20 0.43
CYP2D6 P10635 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
GRM6 O15303 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
CA12 O43570 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethyl Acetate SCHEMBL28944126 0.87 TSHR (0.52) ALDH1A1LMNAHSD17B10TSHRCASP1
Chlorobenzene SCHEMBL16616568 0.86 ALDH1A1 (0.56) ALDH1A1LMNAHSD17B10TSHRMAPT
Chlorobenzene SCHEMBL15562499 0.86 ALDH1A1 (0.56) ALDH1A1LMNAHSD17B10TSHRMAPT
Chlorobenzene SCHEMBL18834102 0.86 ALDH1A1 (0.56) ALDH1A1LMNAHSD17B10TSHRMAPT
Ethyl Acetate SCHEMBL28268414 0.86 TSHR (0.50) ALDH1A1LMNAHSD17B10TSHRCASP1
Naphthalene SCHEMBL27267438 0.83 ALDH1A1 (0.64) ALDH1A1LMNAHSD17B10TSHRMAPT
1,4-Dichlorobenzene SCHEMBL28155008 0.83 ALDH1A1 (0.64) ALDH1A1LMNAHSD17B10TSHRMAPT
O-Xylene SCHEMBL3225611 0.83 ALDH1A1 (0.64) ALDH1A1LMNAHSD17B10TSHRNLRP3
Ethyl Acetate SCHEMBL29014949 0.82 LMNA (0.54) ALDH1A1LMNATSHRMAPTCYP1A2
O-Xylene SCHEMBL27854613 0.82 ALDH1A1 (0.56) ALDH1A1LMNAHSD17B10TSHRNLRP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230403927-A1 AROMATIC COMPOUNDS UDC IRELAND LTD (IE) 2023-12-14 US disclosed
US-11800787-B2 Metal complexes UDC IRELAND LIMITED (IE) 2023-10-24 US disclosed
US-20210351363-A1 ORGANIC THIN FILM TRANSISTOR, ORGANIC SEMICONDUCTOR FILM, COMPOUND, ORGANIC THIN FILM TRANSISTOR-FORMING COMPOSITION, AND METHOD OF MANUFACTURING ORGANIC THIN FILM TRANSISTOR FUJIFILM CORPORATION (JP) 2021-11-11 US disclosed
EP-3476845-B1 ORGANIC THIN-FILM TRANSISTOR, ORGANIC SEMICONDUCTOR FILM, COMPOUND, ORGANIC-THIN-FILM-TRANSISTOR COMPOSITION, AND ORGANIC-THIN-FILM-TRANSISTOR MANUFACTURING METHOD FUJIFILM CORP (JP) 2021-07-21 EP disclosed
CN-109715685-A Marresistance applies material firmly 日产化学株式会社 2019-05-03 CN disclosed
EP-3476845-A1 ORGANIC THIN-FILM TRANSISTOR, ORGANIC SEMICONDUCTOR FILM, COMPOUND, ORGANIC-THIN-FILM-TRANSISTOR COMPOSITION, AND ORGANIC-THIN-FILM-TRANSISTOR MANUFACTURING METHOD FUJIFILM Corporation (JP) 2019-05-01 EP disclosed
CN-107033297-B Siliceous hyper branched polymer and solidification compound containing the polymer 日产化学工业株式会社 2019-04-30 CN disclosed
CN-105566219-B The manufacturing method and its manufacture intermediate of 3,4- dihydroisoquinoline derivatives 三井化学AGRO株式会社 2019-03-01 CN disclosed
CN-108473399-A Novel fluorine compound with unsaturated bond and the surface modifier for having used the fluorochemical 东曹精细化工株式会社 2018-08-31 CN disclosed
CN-105439951-B The manufacturing method of the manufacture intermediate of 3,4- dihydroisoquinoline derivatives 三井化学AGRO株式会社 2018-07-06 CN disclosed
CN-106536575-A Polymer, composition, optical film, and liquid crystal display 富士胶片株式会社 2017-03-22 CN disclosed
CN-102459290-B Electronic devices comprising novel phosphonic acid surface modifiers 乔治亚州技术研究公司 2017-03-22 CN disclosed
EP-2703388-A1 COMPOUND WITH ACRIDAN RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2014-03-05 EP disclosed
US-20140042425-A1 COMPOUND HAVING ACRIDAN RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2014-02-13 US disclosed
CN-1066720-C Process for preparing compounds having pharmacological activity on the central nervous system WELLCOME FOUND (GB) 2001-06-06 CN disclosed
CN-1066719-C Process for preparing compounds having pharmacological activity on the central nervous system WELLCOME FOUND (GB) 2001-06-06 CN disclosed
CN-1115756-A Method for preparing pharmaceutically active CNS compounds WELLCOME FOUND (GB) 1996-01-31 CN disclosed
CN-1113487-A Method for preparing pharmaceutically active CNS compounds WELLCOME FOUND (GB) 1995-12-20 CN disclosed
US-5097074-A Dissolving in aqueous base, precipitating mono-salt by salting out, separating salt from aqueous phase, acidifying KONISHI CHEMICAL INDUSTRY, LIMITED (JP) 1992-03-17 US disclosed
CN-1052306-A Compounds having pharmacological activity on the central nervous system WELLCOME FOUND (GB) 1991-06-19 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230403927-A1 AROMATIC COMPOUNDS TYR, CTCF, MITF ALDH1A1 1461/4885LMNA 3401/4885HSD17B10 3224/4885
US-20210351363-A1 ORGANIC THIN FILM TRANSISTOR, ORGANIC SEMICONDUCTOR FILM, COMPOUND, ORGANIC THIN FILM TRANSISTOR-FORMING COMPOSITION, AND METHOD OF MANUFACTURING ORGANIC THIN FILM TRANSISTOR OSTC, FTO, PORCN ALDH1A1 3800/4885LMNA 4170/4885HSD17B10 3007/4885
US-11800787-B2 Metal complexes AP1M1, SOD1, AP3M1 ALDH1A1 3771/4885LMNA 4079/4885HSD17B10 3051/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.