Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.57 |
| ▸ | DRD1 | P21728 | 2/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | DRD5 | P21918 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30882630 | 1.00 | DRD2 (0.57) | DRD2DRD1TAAR1CHRM2CHRM1 | |
| SCHEMBL10534002 | 0.93 | OPRK1 (0.54) | DRD2DRD1TAAR1CHRM2CHRM1 | |
| SCHEMBL9714684 | 0.89 | DRD2 (0.53) | DRD2DRD1TAAR1CHRM2CHRM1 | |
| SCHEMBL11219508 | 0.87 | MGLL (0.55) | DRD2DRD1TAAR1CHRM2CHRM1 | |
| SCHEMBL21397284 | 0.85 | MGLL (0.58) | DRD2DRD1TAAR1CHRM2CHRM1 | |
| SCHEMBL28507389 | 0.85 | MGLL (0.58) | DRD2DRD1TAAR1CHRM2CHRM1 | |
| SCHEMBL5833923 | 0.85 | MGLL (0.58) | DRD2DRD1TAAR1CHRM2CHRM1 | |
| SCHEMBL19258592 | 0.85 | MEN1 (0.43) | DRD2DRD1TAAR1CHRM2CHRM1 | |
| SCHEMBL350297 | 0.81 | ENPP2 (0.56) | DRD2DRD1TAAR1CHRM2CHRM1 | |
| SCHEMBL723832 | 0.80 | DRD2 (0.74) | DRD2DRD1TAAR1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10787484-B2 | Compositions and methods for treating cardiovascular disease | GENENTECH, INC. (US) | 2020-09-29 | — | — | US | claimed |
| CN-110627832-A | Preparation method for synthesizing tenofovir alafenamide by oxidation method | 江西农业大学 | 2019-12-31 | — | — | CN | claimed |
| US-20190177366-A1 | COMPOSITIONS AND METHODS FOR TREATING CARDIOVASCULAR DISEASE | GENENTECH, INC. (US) | 2019-06-13 | — | — | US | claimed |
| CN-104508116-A | Pesticidal flavobacterium strains and bioactive compositions, metabolites and uses | MARRONE BIO INNOVATIONS INC | 2015-04-08 | — | — | CN | claimed |
| EP-2847318-A1 | PESTICIDAL FLAVOBACTERIUM STRAIN AND BIOACTIVE COMPOSITIONS, METABOLITES AND USES | Marrone Bio Innovations, Inc. (US) | 2015-03-18 | — | — | EP | claimed |
| US-20150031534-A1 | PESTICIDAL FLAVOBACTERIUM STRAIN AND BIOACTIVE COMPOSITIONS METABOLITES AND USES | PRO FARM GROUP, INC. | 2015-01-29 | — | — | US | claimed |
| WO-2013138398-A1 | PESTICIDAL FLAVOBACTERIUM STRAIN AND BIOACTIVE COMPOSITIONS, METABOLITES AND USES | MARRONE BIO INNOVATIONS, INC. (US) | 2013-09-19 | — | — | WO | claimed |
| CN-102936191-A | Method for preparing 3-hydroxy phenylpropyl aldehyde from cinnamyl aldehyde | UNIV GUANGXI NATIONALITIES | 2013-02-20 | — | — | CN | claimed |
| EP-2210900-A2 | Analogues of GLP-1 | IPSEN PHARMA (FR) | 2010-07-28 | — | — | EP | claimed |
| US-20090300800-A1 | D-Amino Acid a Selectable Marker for Barley (Hordeum Vulgare L.) Transformation | BASF PLANT SCIENCE GMBH (DE) | 2009-12-03 | — | — | US | claimed |
| WO-2005058955-A1 | ANALOGUES OF GLP-1 | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A.S. (FR) | 2005-06-30 | — | — | WO | claimed |
| EP-0929574-B1 | MODULATORS OF beta-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS | PRAECIS PHARM INC (US) | 2005-06-29 | — | — | EP | claimed |
| US-20020103134-A1 | Modulators of beta-amyloid peptide aggregation comprising D-amino acids | PRAECIS PHARMACEUTICALS INC. | 2002-08-01 | — | — | US | claimed |
| US-5985242-A | PEPTIDE OF 3 TO 5 D-AMINO ACIDS; MAY BE MODIFIED AT AMINO-AND/OR CARBOXY TERMINUS; FOR TREATMENT OF AMYLOIDOSIS, ALZHEIMER'S DISEASE | PRAECIS PHARMACEUTICALS, INC. (US) | 1999-11-16 | — | — | US | claimed |
| EP-0929574-A1 | MODULATORS OF beta-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS | Praecis Pharmaceuticals Incorporated (US) | 1999-07-21 | — | — | EP | claimed |
| WO-1998008868-A9 | MODULATORS OF β-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS | — | 1998-05-28 | — | — | WO | claimed |
| WO-1998008868-A1 | MODULATORS OF β-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 1998-03-05 | — | — | WO | claimed |
| EP-0297435-B1 | AMINOPROPANOL DERIVATIVES OF 3-(3'-HYDROXYPHENYL)-1-PROPANONE, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | Helopharm W. Petrik GmbH & Co.KG. (DE) | 1991-10-16 | — | — | EP | claimed |
| EP-0297435-A2 | Aminopropanol derivatives of 3-(3'-hydroxyphenyl)-1-propanone, process for their preparation and medicines containing these compounds | Helopharm W. Petrik GmbH & Co.KG. (DE) | 1989-01-04 | — | — | EP | claimed |
| EP-0296265-A1 | Aminopropanol derivatives of 3-(3-hydroxyphenyl)-1-propanone, process for their preparation and medicines containing these compounds | Helopharm W. Petrik GmbH & Co.KG. (DE) | 1988-12-28 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020103134-A1 | Modulators of beta-amyloid peptide aggregation comprising D-amino acids | IAPP, APP, VIP | DRD2 517/4885DRD1 533/4885TAAR1 4007/4885 |
| US-20150031534-A1 | PESTICIDAL FLAVOBACTERIUM STRAIN AND BIOACTIVE COMPOSITIONS METABOLITES AND USES | BLVRB, PRDX6, ACHE | DRD2 2889/4885DRD1 3037/4885TAAR1 1632/4885 |
| US-10787484-B2 | Compositions and methods for treating cardiovascular disease | PCSK9, PCSK7, PCSK6 | DRD2 4852/4885DRD1 4870/4885TAAR1 4623/4885 |
| US-20190177366-A1 | COMPOSITIONS AND METHODS FOR TREATING CARDIOVASCULAR DISEASE | PCSK9, PCSK7, PCSK6 | DRD2 4852/4885DRD1 4870/4885TAAR1 4623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.