Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | TSPO | P30536 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714971 | 0.87 | TSPO (0.46) | TSPO | |
| Hydrochloric Acid SCHEMBL9714930 | 0.86 | LMNA (0.41) | LMNAKDM4EALPLTYMP | |
| SCHEMBL9715039 | 0.84 | LMNA (0.42) | LMNAKDM4EHPGDHSD17B10ALPL | |
| SCHEMBL9714924 | 0.78 | HSD17B10 (0.41) | LMNAKDM4ECYP3A4HPGDHSD17B10 | |
| SCHEMBL9715021 | 0.78 | PTGDR2 (0.39) | KDM4EHPGDALPLTSPOSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9714965 | 0.78 | RAB9A (0.53) | LMNAKDM4EHPGDHSD17B10ALPL | |
| Hydrochloric Acid SCHEMBL9714991 | 0.78 | HSD17B10 (0.40) | LMNAKDM4ECYP3A4HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL9715064 | 0.77 | PTGDR2 (0.39) | KDM4EHPGDALPLTSPOSMN1; SMN2 | |
| SCHEMBL9714951 | 0.75 | P2RX7 (0.39) | KDM4ETSPOSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9714943 | 0.69 | L3MBTL1 (0.45) | KDM4ECYP3A4HPGDHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992018484-A1 | 3-AMINO-5-ARYLPYRAZOLE-4-ACETIC ACID DERIVATIVES EXHIBITING THERAPEUTIC EFFECTS | A.H. ROBINS COMPANY, INCORPORATED (US) | 1992-10-29 | — | — | WO | claimed |
| US-5057534-A | Anxiolytic, anticonfulsant and muscle relaxants | A. H. ROBINS COMPANY INCORPORATED (US) | 1991-10-15 | — | — | US | claimed |
| WO-1992018484-A1 | 3-AMINO-5-ARYLPYRAZOLE-4-ACETIC ACID DERIVATIVES EXHIBITING THERAPEUTIC EFFECTS | A.H. ROBINS COMPANY, INCORPORATED (US) | 1992-10-29 | — | — | WO | disclosed |