SCHEMBL9716564

SCHEMBL9716564

CCC(c1ccccc1)[Si](CC)(OC)OC

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.41
KMT2A Q03164 2/20 0.35
POLB P06746 2/20 0.35
MEN1 O00255 1/20 0.35
HTT P42858 1/20 0.35
TSHR P16473 1/20 0.35
HTR2A P28223 1/20 0.34
HRH1 P35367 1/20 0.34
MIF P14174 1/20 0.34
TRPA1 O75762 3/20 0.33
TAAR1 Q96RJ0 1/20 0.33
TP53 P04637 1/20 0.33
HKDC1 Q2TB90 1/20 0.33
AOC3 Q16853 1/20 0.33
NOS3 P29474 1/20 0.33
NOS2 P35228 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2822248 0.80 LMNA (0.43) LMNAKMT2APOLBMEN1HTT
SCHEMBL9716583 0.80 LMNA (0.43) LMNAKMT2APOLBMEN1HTT
SCHEMBL9716573 0.78 TAAR1 (0.38) LMNAKMT2AHTTTRPA1TAAR1
SCHEMBL9716576 0.78 LMNA (0.42) LMNAKMT2APOLBMEN1HTT
SCHEMBL12999580 0.78 LMNA (0.42) LMNAKMT2APOLBMEN1HTT
SCHEMBL4058170 0.77 LMNA (0.41) LMNAKMT2APOLBMEN1HTT
SCHEMBL19809402 0.77 LMNA (0.45) LMNAKMT2APOLBTSHRTRPA1
SCHEMBL28159957 0.73 KDM4E (0.34) LMNAKMT2APOLBMEN1HTT
SCHEMBL22283489 0.71 LMNA (0.46) LMNAKMT2APOLBMEN1HTT
SCHEMBL3794550 0.71 LMNA (0.46) LMNAKMT2APOLBMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1036202-C Polymerization catalyst MITSUI PETROCHEMICAL IND (JP) 1997-10-22 CN disclosed
CN-1117055-A Polymerization catalyst MITSUI PETROCHEMICAL IND (JP) 1996-02-21 CN disclosed
CN-1030990-C Olefin polymerization process MITSUI PETROCHEMICAL IND (JP) 1996-02-14 CN disclosed
EP-0282341-B1 PROCESS FOR POLYMERIZATION OF OLEFINS AND POLYMERIZATION CATALYST MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-05-20 EP disclosed
EP-0455313-A1 Process for polymerization of olefins and polymerization catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-11-06 EP disclosed
US-5028671-A Using coordination catalyst contining magnesium, titanium, halogen compounds with organoaluminum and organosilicon compounds MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-07-02 US disclosed
CN-88101916-A Olefin polymerization process and catalyst therefor 1988-10-26 CN disclosed
EP-0282341-A1 Process for polymerization of olefins and polymerization catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-09-14 EP disclosed