SCHEMBL4058170

SCHEMBL4058170

CCC(c1ccccc1)[Si]([O])(OC)OC

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.41
KMT2A Q03164 3/20 0.39
POLB P06746 2/20 0.39
TSHR P16473 2/20 0.39
MEN1 O00255 2/20 0.39
HTT P42858 2/20 0.39
HSD17B10 Q99714 2/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
MIF P14174 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
CYP2C9 P11712 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9716583 0.80 LMNA (0.43) LMNAKMT2APOLBTSHRMEN1
SCHEMBL2822248 0.80 LMNA (0.43) LMNAKMT2APOLBTSHRMEN1
SCHEMBL22283489 0.79 LMNA (0.46) LMNAKMT2APOLBTSHRMEN1
SCHEMBL9716576 0.78 LMNA (0.42) LMNAKMT2APOLBTSHRMEN1
SCHEMBL12999580 0.78 LMNA (0.42) LMNAKMT2APOLBTSHRMEN1
SCHEMBL4494436 0.78 LMNA (0.45) LMNAKMT2APOLBTSHRMEN1
SCHEMBL9716564 0.77 LMNA (0.41) LMNAKMT2APOLBTSHRMEN1
SCHEMBL9745875 0.71 LMNA (0.52) LMNAKMT2APOLBTSHRMEN1
SCHEMBL3794550 0.71 LMNA (0.46) LMNAKMT2APOLBTSHRMEN1
SCHEMBL20994305 0.71 KMT2A (0.38) KMT2APOLBTSHRALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1863875-B1 SELF-ADHESIVE ADDITION CROSS LINKING SILICON-RUBBER BLENDS, METHOD FOR THE PRODUCTION THEREOF, METHOD FOR PRODUCING COMPOSITE MOULDED PARTS AND THE USE THEREOF MOMENTIVE PERFORMANCE MAT INC (DE) 2009-12-09 EP claimed
US-20090068475-A1 Self-Adhesive Addition-Crosslinking Silicon Rubber Blends, A Method For The Production Thereof, Methods For Producing Composite Moulded Parts And The Use Thereof MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2009-03-12 US claimed
US-20090068475-A1 Self-Adhesive Addition-Crosslinking Silicon Rubber Blends, A Method For The Production Thereof, Methods For Producing Composite Moulded Parts And The Use Thereof MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2009-03-12 US disclosed