SCHEMBL9716583

SCHEMBL9716583

CCC(c1ccccc1)[Si](OC)(OC)C(CC)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.43
KMT2A Q03164 2/20 0.37
TSHR P16473 2/20 0.37
POLB P06746 1/20 0.37
MEN1 O00255 1/20 0.37
HTT P42858 1/20 0.37
MIF P14174 1/20 0.36
MTOR P42345 1/20 0.35
RAB9A P51151 1/20 0.35
GRM7 Q14831 1/20 0.35
TRPA1 O75762 2/20 0.35
HKDC1 Q2TB90 1/20 0.35
TACR3 P29371 2/20 0.35
TACR2 P21452 1/20 0.35
TAAR1 Q96RJ0 2/20 0.34
HTR2A P28223 1/20 0.34
HRH1 P35367 1/20 0.34
CYP3A4 P08684 1/20 0.34
ALOX15 P16050 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2822248 0.83 LMNA (0.43) LMNAKMT2ATSHRPOLBMEN1
SCHEMBL9716576 0.82 LMNA (0.42) LMNAKMT2ATSHRPOLBMEN1
SCHEMBL12999580 0.82 LMNA (0.42) LMNAKMT2ATSHRPOLBMEN1
SCHEMBL9716564 0.80 LMNA (0.41) LMNAKMT2ATSHRPOLBMEN1
SCHEMBL4058170 0.80 LMNA (0.41) LMNAKMT2ATSHRPOLBMEN1
SCHEMBL9745875 0.74 LMNA (0.52) LMNAKMT2ATSHRPOLBMEN1
SCHEMBL22283489 0.74 LMNA (0.46) LMNAKMT2ATSHRPOLBMEN1
SCHEMBL3794550 0.74 LMNA (0.46) LMNAKMT2ATSHRPOLBMEN1
SCHEMBL20658076 0.73 LMNA (0.42) LMNAKMT2APOLBMEN1HTT
SCHEMBL4494436 0.72 LMNA (0.45) LMNAKMT2ATSHRPOLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0282341-B1 PROCESS FOR POLYMERIZATION OF OLEFINS AND POLYMERIZATION CATALYST MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-05-20 EP disclosed
EP-0455313-A1 Process for polymerization of olefins and polymerization catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-11-06 EP disclosed
US-5028671-A Using coordination catalyst contining magnesium, titanium, halogen compounds with organoaluminum and organosilicon compounds MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-07-02 US disclosed