SCHEMBL9716573

SCHEMBL9716573

CC[Si](OC)(OC)C(C)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.38
LMNA P02545 1/20 0.38
TRPA1 O75762 5/20 0.37
HTT P42858 1/20 0.36
SIGMAR1 Q99720 1/20 0.35
CASR P41180 1/20 0.35
TP53 P04637 1/20 0.34
KMT2A Q03164 1/20 0.34
AOC3 Q16853 1/20 0.34
HKDC1 Q2TB90 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19809402 0.78 LMNA (0.45) LMNATRPA1KMT2AAOC3
SCHEMBL9716564 0.78 LMNA (0.41) TAAR1LMNATRPA1HTTTP53
SCHEMBL28159957 0.74 KDM4E (0.34) LMNATRPA1HTTTP53KMT2A
SCHEMBL140535 0.74 TRPA1 (0.39) TAAR1LMNATRPA1KMT2A
SCHEMBL9716601 0.74 KMT2A (0.39) TAAR1LMNATRPA1HTTSIGMAR1
SCHEMBL19816718 0.73 CA4 (0.37) TAAR1LMNASIGMAR1CASRTP53
SCHEMBL3084097 0.72 FAAH (0.38) TAAR1LMNATRPA1KMT2A
SCHEMBL6890013 0.72 FAAH (0.38) TAAR1LMNATRPA1KMT2A
Methane SCHEMBL28677698 0.72 TAAR1 (0.41) TAAR1LMNATRPA1KMT2AAOC3
SCHEMBL14841788 0.72 KDM4E (0.33) LMNATRPA1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1036202-C Polymerization catalyst MITSUI PETROCHEMICAL IND (JP) 1997-10-22 CN disclosed
CN-1117055-A Polymerization catalyst MITSUI PETROCHEMICAL IND (JP) 1996-02-21 CN disclosed
CN-1030990-C Olefin polymerization process MITSUI PETROCHEMICAL IND (JP) 1996-02-14 CN disclosed
EP-0282341-B1 PROCESS FOR POLYMERIZATION OF OLEFINS AND POLYMERIZATION CATALYST MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-05-20 EP disclosed
EP-0455313-A1 Process for polymerization of olefins and polymerization catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-11-06 EP disclosed
US-5028671-A Using coordination catalyst contining magnesium, titanium, halogen compounds with organoaluminum and organosilicon compounds MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-07-02 US disclosed
CN-88101916-A Olefin polymerization process and catalyst therefor 1988-10-26 CN disclosed
EP-0282341-A1 Process for polymerization of olefins and polymerization catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-09-14 EP disclosed