SCHEMBL9716576

SCHEMBL9716576

CCC(c1ccccc1)[Si](C)(OC)OC

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.42
KMT2A Q03164 2/20 0.36
POLB P06746 1/20 0.36
MEN1 O00255 1/20 0.36
HTT P42858 1/20 0.36
TSHR P16473 1/20 0.36
MIF P14174 1/20 0.35
CYP2C9 P11712 4/20 0.35
TRPA1 O75762 2/20 0.34
HKDC1 Q2TB90 1/20 0.34
S1PR1 P21453 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12999580 0.84 LMNA (0.42) LMNAKMT2APOLBMEN1HTT
SCHEMBL9716567 0.82 LMNA (0.41) LMNAKMT2APOLBMEN1HTT
SCHEMBL9716583 0.82 LMNA (0.43) LMNAKMT2APOLBMEN1HTT
SCHEMBL2822248 0.82 LMNA (0.43) LMNAKMT2APOLBMEN1HTT
SCHEMBL4058170 0.78 LMNA (0.41) LMNAKMT2APOLBMEN1HTT
SCHEMBL9716564 0.78 LMNA (0.41) LMNAKMT2APOLBMEN1HTT
SCHEMBL8051709 0.78 KMT2A (0.31) KMT2APOLB
SCHEMBL523287 0.75 LMNA (0.45) LMNAKMT2APOLBMEN1TSHR
SCHEMBL4494436 0.75 LMNA (0.45) LMNAKMT2APOLBMEN1HTT
SCHEMBL661362 0.74 LMNA (0.41) LMNAKMT2APOLBMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0282341-B1 PROCESS FOR POLYMERIZATION OF OLEFINS AND POLYMERIZATION CATALYST MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-05-20 EP disclosed
EP-0455313-A1 Process for polymerization of olefins and polymerization catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-11-06 EP disclosed
US-5028671-A Using coordination catalyst contining magnesium, titanium, halogen compounds with organoaluminum and organosilicon compounds MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-07-02 US disclosed
EP-0282341-A1 Process for polymerization of olefins and polymerization catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-09-14 EP disclosed