Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | AR | P10275 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | SPR | P35270 | 1/20 | 0.53 |
| ▸ | GSTA1 | P08263 | 2/20 | 0.50 |
| ▸ | LIG1 | P18858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2167285 | 0.89 | LMNA (0.62) | LMNACYP1A2PGRCYP3A4ADORA3 | |
| SCHEMBL14274483 | 0.87 | NPC1 (0.54) | RAB9AKMT2AALDH1A1NFE2L2NPC1 | |
| SCHEMBL11756227 | 0.87 | MAPK13 (0.53) | RAB9AKMT2AALDH1A1NFE2L2NPC1 | |
| SCHEMBL12909853 | 0.86 | ALDH1A1 (0.51) | LMNACYP1A2PGRCYP3A4ADORA3 | |
| SCHEMBL5962983 | 0.85 | GSTA1 (0.62) | LMNACYP1A2PGRCYP3A4ADORA3 | |
| SCHEMBL11057757 | 0.85 | CSNK2A1 (0.60) | CYP1A2HPGDALOX15CYP2C19RAB9A | |
| SCHEMBL31369141 | 0.84 | LMNA (0.50) | LMNACYP1A2CYP3A4CYP2C19RAB9A | |
| SCHEMBL286054 | 0.84 | LMNA (0.50) | LMNACYP1A2CYP3A4CYP2C19RAB9A | |
| SCHEMBL3358950 | 0.83 | SPR (0.56) | LMNACYP1A2PGRCYP3A4ADORA3 | |
| SCHEMBL5709905 | 0.82 | KMT2A (0.53) | LMNAHPGDRAB9AHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0499450-A1 | Synthesis of 1-aminoanthraquinone | HOECHST CELANESE CORPORATION (US) | 1992-08-19 | — | — | EP | disclosed |
| US-5130448-A | Condensing ortho substituted benzoic acid and xylene, oxidation, ring closure, ammonolysis and decarboxyalation | HOECHST CELANESE CORPORATION (US) | 1992-07-14 | — | — | US | disclosed |