Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL263454 | 0.81 | KDM4E (0.32) | KDM4EMAPK1HIF1A | |
| SCHEMBL12451661 | 0.80 | KDM4E (0.52) | KDM4EMAPK1HIF1A | |
| SCHEMBL514781 | 0.80 | KDM4E (0.31) | KDM4EMAPK1HIF1A | |
| SCHEMBL9717462 | 0.80 | CCR2 (0.40) | — | |
| SCHEMBL13464622 | 0.78 | KDM4E (0.44) | KDM4EMAPK1HIF1A | |
| SCHEMBL1402612 | 0.77 | KDM4E (0.32) | KDM4EMAPK1HIF1A | |
| SCHEMBL10751335 | 0.77 | KDM4E (0.35) | KDM4EMAPK1HIF1A | |
| Acrylamide SCHEMBL2476543 | 0.76 | ALDH1A1 (0.31) | — | |
| SCHEMBL13612101 | 0.76 | MEN1 (0.36) | — | |
| SCHEMBL515437 | 0.75 | KDM4E (0.34) | KDM4EMAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162391-A | Copolymer of Siloxanyalkylacrylamide of a Fluoro Monomer | KURARAY CO., LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0387706-A2 | Oxygen permeable hard contact lens | KURARAY CO., LTD. (JP) | 1990-09-19 | — | — | EP | disclosed |