SCHEMBL9717462

SCHEMBL9717462

CCCCCCCC=C(C)C(=O)NCCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CCR2 P41597 1/20 0.40
EPHX2 P34913 5/20 0.38
EPHX1 P07099 5/20 0.36
EP300 Q09472 1/20 0.36
FAAH O00519 1/20 0.35
ZDHHC20 Q5W0Z9 1/20 0.35
ZDHHC2 Q9UIJ5 1/20 0.35
PLA2G2A P14555 1/20 0.35
PLA2G4A P47712 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9717442 0.80 KDM4E (0.31)
SCHEMBL25323636 0.77
Dimethylamine SCHEMBL8427223 0.77 EPHX1 (0.46) CCR2EPHX2EPHX1EP300PLA2G2A
SCHEMBL14691621 0.77 CNR1 (0.50) EP300FAAH
SCHEMBL28788568 0.76 EPHX2 (0.46) EPHX2EPHX1ZDHHC20ZDHHC2PLA2G2A
SCHEMBL9717447 0.76 PLA2G2A (0.42) EPHX2EPHX1FAAHZDHHC20ZDHHC2
SCHEMBL647032 0.75 EP300 (0.48) CCR2EPHX1EP300FAAHPLA2G2A
SCHEMBL9717454 0.73 CCR2 (0.39) CCR2EP300FAAH
SCHEMBL8407722 0.72 ACHE (0.66) EPHX2EPHX1
SCHEMBL809437 0.72 TBXAS1 (0.33) EP300

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5162391-A Copolymer of Siloxanyalkylacrylamide of a Fluoro Monomer KURARAY CO., LTD. (JP) 1992-11-10 US disclosed