SCHEMBL9717447

SCHEMBL9717447

C=C(CCCCCCCCCCCC)C(=O)NCCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 3/20 0.42
PLA2G4A P47712 1/20 0.42
EPHX1 P07099 6/20 0.38
CASP2 P42575 1/20 0.38
FAAH O00519 5/20 0.38
EPHX2 P34913 1/20 0.37
ZDHHC20 Q5W0Z9 1/20 0.36
ZDHHC2 Q9UIJ5 1/20 0.36
NAAA Q02083 1/20 0.36
DNM1 Q05193 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7161002 0.82 PLA2G2A (0.59) PLA2G2APLA2G4AEPHX1CASP2FAAH
SCHEMBL263454 0.77 KDM4E (0.32)
SCHEMBL514781 0.76 KDM4E (0.31)
SCHEMBL9717462 0.76 CCR2 (0.40) PLA2G2APLA2G4AEPHX1FAAHEPHX2
SCHEMBL14138655 0.75 CASP2 (0.60) PLA2G2APLA2G4AEPHX1CASP2FAAH
SCHEMBL10748964 0.75 ACHE (0.32)
SCHEMBL10751317 0.75 ACHE (0.32)
SCHEMBL8407722 0.74 ACHE (0.66) EPHX1EPHX2
SCHEMBL6280150 0.74 NAAA (0.56) PLA2G2APLA2G4AEPHX1CASP2EPHX2
SCHEMBL720662 0.73 FAAH (0.59) PLA2G2AFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5162391-A Copolymer of Siloxanyalkylacrylamide of a Fluoro Monomer KURARAY CO., LTD. (JP) 1992-11-10 US disclosed