Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | S100A4 | P26447 | 2/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8208233 | 0.83 | TDP1 (0.48) | ALDH1A1TDP1NPC1RAB9ARECQL | |
| SCHEMBL1424469 | 0.82 | ALDH1A1 (0.58) | ALDH1A1TDP1NPC1RAB9ARECQL | |
| SCHEMBL29509634 | 0.81 | HSPB1 (0.45) | ALDH1A1TDP1NPC1RAB9ARECQL | |
| SCHEMBL12480460 | 0.81 | HSPB1 (0.45) | ALDH1A1TDP1NPC1RAB9ARECQL | |
| SCHEMBL12475795 | 0.80 | TDP1 (0.58) | ALDH1A1TDP1NPC1RAB9ARECQL | |
| SCHEMBL846126 | 0.80 | GPR35 (0.58) | ALDH1A1TDP1NPC1RAB9ARECQL | |
| SCHEMBL9118851 | 0.80 | TDP1 (0.43) | ALDH1A1TDP1NPC1RAB9ARECQL | |
| SCHEMBL18246234 | 0.78 | DRD1 (0.39) | ALDH1A1L3MBTL1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL1059260 | 0.77 | ALDH1A1 (0.67) | ALDH1A1TDP1NPC1RAB9ARECQL | |
| SCHEMBL5699210 | 0.77 | TDP1 (0.41) | ALDH1A1TDP1NPC1RAB9ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524896-B2 | Chemical compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-09-03 | — | — | US | disclosed |
| US-8524896-B2 | Chemical compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-09-03 | — | — | US | disclosed |
| EP-2500340-A1 | 2-Cyanophenyl Sulfonamide Derivatives Useful as Pesticides | Syngenta Participations AG. (CH) | 2012-09-19 | — | — | EP | disclosed |
| EP-2500340-A1 | 2-Cyanophenyl Sulfonamide Derivatives Useful as Pesticides | Syngenta Participations AG. (CH) | 2012-09-19 | — | — | EP | disclosed |
| CN-101965332-A | 2-cyanobenzenesulfonamide derivatives having pesticidal properties | SYNGENTA CROP PROT INC | 2011-02-02 | — | — | CN | disclosed |
| US-20110009261-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-01-13 | — | — | US | disclosed |
| US-20110009261-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-01-13 | — | — | US | disclosed |
| EP-2265579-A2 | 2-CYANOBENZENSULFONAMIDE DERIVATIVES HAVING PESTICIDAL PROPERTIES | Syngenta Participations AG (CH) | 2010-12-29 | — | — | EP | disclosed |
| US-20100311582-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-12-09 | — | — | US | disclosed |
| US-20100311582-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-12-09 | — | — | US | disclosed |
| EP-2231632-A2 | 2-CYANOPHENYL SULFONAMIDE DERIVATIVES USEFUL AS PESTICIDES | Syngenta Participations AG (CH) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009109539-A2 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-09-11 | — | — | WO | disclosed |
| WO-2009109539-A2 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-09-11 | — | — | WO | disclosed |
| WO-2009092590-A2 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-07-30 | — | — | WO | disclosed |
| WO-2009092590-A2 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-07-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009261-A1 | CHEMICAL COMPOUNDS | CBR3, CBR1, CYCS | ALDH1A1 3381/4885TDP1 3742/4885NPC1 1533/4885 |
| US-20100311582-A1 | CHEMICAL COMPOUNDS | CBR3, CBR1, CCNY | ALDH1A1 3581/4885TDP1 4036/4885NPC1 787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.